Latest - Transplantation

 
 
  • The Microbiome: It's What's Inside That Counts   The microbiome is the constellation of microscopic organisms that call the human body home, and its clinical implications are becoming increasingly clear to physicians.
  • Jan 05 2024 This Week in Cardiology   Neuro-modulation in HF, private equity owned hospitals, HCM, SCD and ICD re-evaluated, and peer review are the topics John Mandrola, MD, discusses in this week's podcast.
  • Newborn Recipient of Partial Heart Transplant Doing Well The world's first transplantation of aortic and pulmonary valves into a neonate delivered a good outcome, and the valves showed continued adaptive growth and function.
  • Elafibranor Appears Effective, Safe for PBC Treatment with elafibranor showed significantly greater improvements in relevant biochemical indicators of cholestasis than the placebo.
  • Record-High Wait Lists for Cancer, Other Surgeries in Quebec The passage of Bill 15, a wide-ranging healthcare reform proposal, could provide relief but not in the short term.
  • Alert FDA Expands Label for CVRx Barostim System in HF The Barostim neuromodulation system is now indicated in NYHA class III or class II HF despite guideline-directed medical therapies, with LVEF ≤ 35% and NT-proBNP < 1600 pg/mL.
  • The 2024 Adult Vaccine Schedule Changes Are Here   Usually posted in February, the 2024 schedule has arrived early. Dr Sandra Fryhofer goes over the key changes in the adult schedule for 2024.
  • Lifesaving Surgery for Lungless Man   Surgical creativity and a dash of DIY helped Chicago-area man beat a devastating pulmonary infection that destroyed both of his lungs.
  • Infographic: Can Doctors Meet Retirement Finances Goals? Physicians revealed how big of a retirement nest egg their families want. Doctors, on average, have met 77% of that goal already, so most of them are confident in funding their retirement.
  • ECG Deep-Learning Algorithm Predicts Mortality Post Surgery A novel deep-learning algorithm outperformed a conventional risk score in predicting post-surgery mortality.
  • GVHD Raises Vitiligo Risk in Transplant Recipients "The findings suggest that early detection and management of vitiligo lesions can be improved by estimating the likelihood of its development in transplant recipients..."
  • Infections Down in Acute Care Hospitals Prevention strategies to reduce healthcare-associated infections are having an effect, according to a new report on national- and state-level incidence.
  • Debate Grows Over Facility Fees, Lawmakers Urge Transparency There's continued interest in more transparency about medical costs, in particular facility fees. But there's also a divided opinion about eliminating these payments for US medical care.
  • Top 10 Fictional Docs on Streaming TV Both tried-and-true and out-of-the-ordinary holiday gift ideas are offered to those seeking a great present for a physician.
  • Infographic: Female Physicians Close Their Wealth Gap Female physicians' survey answers about their net worth show a gender gap vs male doctors (although it's narrowing) and reveal their saving and borrowing habits.
  • This Frontline Therapy Is Better in Multiple Myeloma: Study A study directly comparing real-world outcomes suggests patients with transplant-ineligible multiple myeloma do better with frontline triple therapy with daratumumab vs bortezomib.
  • Medscape Physicians Eye Retirement: 2023 Report Physicians of various ages reveal their financial goals for retirement and the personal and professional lifestyles they want to lead after practicing medicine.
  • No Benefit to Salvage Transplant in R/R Multiple Myeloma Long-term follow-up shows no progression-free or overall survival advantage among patients who received salvage transplant vs continuous lenalidomide plus dexamethasone.
  • Medscape Nurse Career Satisfaction Report 2023 Several categories of nurses describe what makes them happiest and unhappiest with their career, how the abuse they experience shapes their views, and other facets of career satisfaction.
  • MRD Status Predicts Transplant Benefit in NPM1-Mutated AML MRD-positive patients in first complete remission after induction therapy had a survival benefit after transplant; however, that benefit did not extend to MRD-negative patients after transplant.
  • Why Are Prion Diseases on the Rise?   Remember the outbreak of "mad cow disease" in the 1990s? Creutzfeldt-Jakob is increasing again, but this time, we don't know why.
  • Report: Kidney Disease Evident in These Eye Issues An analysis of four new studies found that retinal and choroidal thickness in the back of the eye correlates with kidney function in patients with chronic kidney disease.
  • Sickle Cell Gene Therapy 'Truly Transformative' Patients who received lovo-cel had durable remissions and reductions in vaso-occlusive events, pain crises, and hospitalizations in the longest running gene therapy trial for sickle cell disease.
  • This Test May Guide AML Therapy for Black Pediatric Patients A new analysis suggests that a polygenic score can help determine the best drug regimens for young Black patients with AML who often face worse outcomes than White patients.
  • In Real World, Patients With Myeloma Have Worse Outcomes A new analysis found that patients with multiple myeloma receiving standard therapies have much worse outcomes compared with those treated in clinical trials.
  • New Delhi Investigating Alleged Illegal Kidney Transplants The New Delhi city government is investigating an Apollo hospital after a media report linked it to the illegal sale by Myanmar nationals of their kidneys for organ transplants.
  • Change Makers: Bill Meury on Transformative Medicines Bill Meury, president and CEO of Karuna Therapeutics, speaks with WebMD Chief Medical Officer John Whyte, MD, about the differences in drug development in psychiatry and the importance of innovation.
  • How’s the Food? Rate Your Hospital Cafeteria Historically, hospital cafeterias have not been celebrated for the quality of their cuisine, typically feeding their staff from the same kitchen that prepared patient meals. How would you rate your hospital's cafeteria?
  • Radioimmunotherapy Tops ASCT in R/R Follicular Lymphoma A new trial from Italy challenges a decades-old assumption that autologous stem cell transplant is more effective than radioimmunotherapy for consolidation after follicular lymphoma relapse.
  • Medscape Female Physician Wealth & Debt Report 2023 Female physicians discuss their track record in building family net worth and reveal how they feel about their savings, spending, investing, and other aspects of personal finance.
  • France's First Larynx Transplant The patient who received the first larynx transplant to be performed in France is recovering well and beginning to regain the use of her voice.
  • Are You Sure Your Patient Is Alive?   Someone knows when a person has died, but a shocking lack of sharing that news is causing problems for clinicians, families, and health systems.
  • No Benefit of Levothyroxine in Heart Donors New data challenge the common practice of levothyroxine administration in potential heart donors after brain death to preserve heart function and make more hearts available for transplantation.
  • Pig Organs in Humans: We're Not Ready Yet, Says Ethicist   Bioethicist Art Caplan discusses the current status of using of pig organs for transplantation in humans.
  • MSWS 2023 Misdiagnoses Among Challenges in Managing Cutaneous Lymphoma Although predictive tools to identify those at risk of disease progression are in their infancy, the development of such tools is crucial for improving patient outcomes.
  • Infographic: Doctors Grade Their EHR Systems Physicians reveal how well they think their employer's electronic health record (EHR) systems are or aren't delivering on certain key features.
  • ACG 2023 Tool Identifies Alcohol Relapse Risk After Liver Transplant A novel prognostic tool based on social determinants effectively predicted increased risk of alcohol use relapse in adults who underwent liver transplants for alcoholic liver disease.
  • Medscape Physicians and EHRs Report 2023 Physicians reveal how long and how their medical practices have used electronic health records (EHRs), where they have ongoing concerns, and where they hope for improvements in EHR systems.
  • Should Physicians Go to Work When Sick? Although most doctors believe it's best to stay home if they're ill, today's healthcare system makes the answer much more complicated.
  • CAR-T Therapy for NHL Treats Concurrent Rheumatic Disease CAR–T cell therapy for non-Hodgkin lymphoma appeared as safe and effective in patients with rheumatic autoimmune disease as in those without and also improved control of the underlying autoimmunity.